Adaptive Optimal Two Treatment Crossover Designs with Binary Endpoint
Institution: | University of Illinois – Chicago |
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Department: | |
Year: | 2015 |
Keywords: | Adaptive optimal design; crossover design; binary endpoint; sample size reduction; statistical power |
Record ID: | 2061638 |
Full text PDF: | http://hdl.handle.net/10027/19355 |
We develop two-stage two-treatment adaptive optimal (AO) crossover designs with binary endpoint and efficiently reduce the sample size as well as maintain the statistical power.