Two upland cotton varieties (Deltapine 5415 and SureGrow 125) were subjected to various seed fungicide treatments to determine seedling emergence and vigor in a Mohave Valley field prone to Rhizoctonia infection of cotton seedlings. During 1998, cotton seedlings in this field exhibited symptoms associated with Rhizoctonia, Pythium, and Thielaviopsis fungi. Of the treatments examined in this study, Baytan+Thiram+Allegiance or Baytan+Ascend+Allegiance cotton seed treatments provided superior seedling disease protection. The Protégé+Allegiance fungicide treatment provided superior seedling disease protection when applied to Deltapine 5415 cotton seed, however seedling disease suppression was poor when the same treatment was applied to SureGrow 125. The Vitavax-PCNB+Allegiance and NuFlow M+Maxim+Apron were the least effective fungicide seed treatments examined in this study.