AbstractsMedical & Health Science
The action of various hypotensive agents on the urinary excretion of adrenaline and noradrenaline.
| Institution: | McGill University |
|---|---|
| Department: | Department of Health Sciences. |
| Degree: | PhD |
| Year: | 1961 |
| Keywords: | Pharmacology. |
| Record ID: | 1576179 |
| Full text PDF: | http://digitool.library.mcgill.ca/thesisfile113519.pdf |
Abstract
In previous studies from this laboratory, it has been found that certain antisympathomimetic drugs (phenoxybenzamine, piperoxane and chlorpromazine) increase the urinary excretion of adrenaline and noradrenaline and elevate the urinary recovery of intravenously administered adrenaline and noradrenaline (Benfey, Mazurkiewicz and Melville, 1958; and Benfey, Ledoux and Melville, 1958, 1959). This was a surprising result since antisympathomimetic agents have been employed to obtain vasodilatation and reduction of an elevated blood pressure, conditions in which a rise in free adrenaline and noradrenaline in the body are undesired.
