Alkaloids of monimiaceous plants
Institution: | University of Tasmania |
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Department: | |
Year: | 1965 |
Keywords: | Alkaloids; Monimiaceae |
Record ID: | 1568397 |
Full text PDF: | http://eprints.utas.edu.au/19476/1/whole_DouglasGordonKeith1966_thesis.pdf |
Alkaloid-bearing plants of the Australian Monimiaceae have generally yielded alkaloids of the bisbenzylisoquinoline type. For this reason a brief outline of the chemistry of this class of compound will be presented; a more detailed account may be found in a complete and thorough review by Grundonl . The bisbenzylisoquinoline molecule consists of two benzylisoquinoline moieties linked by one, two or three oxygen atoms; these ether bridges are believed to arise by intermolecular dehydrogenation of two molecules of 1-(4-hydroxybenzy1)-6,7-dihydroxy-1,2,3, 4-tetrahydroisoquinoline in which the new C-0 bond is formed by phenolic coupling at nuclear positions ortho to hydroxyl groups. The route which the dehydrogenation follows leads to the classification of bisbenzylisoquinoline alkaloids into several different classes.