Relation of age to the effect of morphine on the metabolism of mouse brain tissue.
Institution: | McGill University |
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Department: | Department of Biochemistry. |
Degree: | MS. |
Year: | 1951 |
Keywords: | Biochemistry. |
Record ID: | 1555943 |
Full text PDF: | http://digitool.library.mcgill.ca/thesisfile119178.pdf |
It is a well established fact that morphine is more toxic to young animals than to old. (see Literature Review, section C-l) Since morphine is known to act on the central nervous system, it was hoped that the investigation of its effects on brain metabolism "in vitro" in relation to age of the animal, might be another step towards the understanding of its mode of action "in vivo". [...]