AbstractsBiology & Animal Science

Staphylococcal alpha haemolysin fractions and a study of their immunological and biological properties.

by Marc. Stanislawski




Institution: McGill University
Department: Department of Biology.
Degree: MS.
Year: 1959
Keywords: Bacteriology and Immunology.
Record ID: 1543740
Full text PDF: http://digitool.library.mcgill.ca/thesisfile112091.pdf


Abstract

The purpose of this investigation was to study the biological and immunological properties of purified preparations of Staphylococcus pyogenes Wood 46 alpha toxin. The toxin was fractionated by carboxymethyl cellulose column chromatography and purified by a zinc-ethanol precipitation technique and the materials tested for functional antigenicity in rabbits. An attempt was made to contribute to the question of unity and diversity of biological activities associated with the alpha haemolysin of Staphylococcus pyogenes using the technique of zone electrophoresis on starch-gel.