AbstractsChemistry

Primary and secondary aliphatic and saturated cyclic amines as well as primary aromatic and heterocyclic amines react with trichloro-, trifluoro-, and dichloro-acetonitriles to give the corresponding amidines. Sixteen trichloro-, seven trifluoro- and five dichloro-acetamidines were prepared by procedures characterized by their simplicity, the absence of catalysts and the high yields of the reaction products. Experimental evidence was produced to support the reaction mechanism and certain limitations to the above mentioned reactions were defined.