AbstractsBiology & Animal Science

Transamination in the mammalian erythrocyte.

by Alfred. Fessler




Institution: McGill University
Department: Department of Chemistry.
Degree: MS.
Year: 1959
Keywords: Biochemistry.
Record ID: 1538527
Full text PDF: http://digitool.library.mcgill.ca/thesisfile111760.pdf


Abstract

The study reported here is part of a larger research project on the preservation of blood which has been in continuous progress in the Department of Biochemistry under the direction of Dr. O. F. Denstedt since the outbreak of World War II. During the trial-and-error phase of the research in the early 1940's, it became evident that in order to do anything about the preservation of red cells it was necessary to know what metabolic systems undergo failure, in order to endeavour to prevent or correct the impairment. Accordingly, the emphasis of the programme was diverted to a study of the enzymology of the red cell and the nature of the changes that occur during storage and ultimately cause loss of function.