The adaptation of kidney tests to small laboratory rodents.
Institution: | McGill University |
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Department: | Department of Anatomy. |
Degree: | PhD |
Year: | 1942 |
Keywords: | Anatomy. |
Record ID: | 1537357 |
Full text PDF: | http://digitool.library.mcgill.ca/thesisfile129745.pdf |
Methods of estimating the excretory capacity of the kidney by the administration of various compounds and the determination of their concentration in the urine have long been in use. The specificity of these tests has increased to the point, where, today, we are able to determine not only the efficiency of the kidney as a whole, but of the various parts of that organ. Some of the earliest tests were performed on man and among these were the observations of Todd (69) and Charcot (5), Roberts (56), Duckworth (13) and Chauvet (7) who published accounts of the excretion, in disease, of various drugs, among which were mercury, iodides, quinine and many others.