METABOLIC STUDIES ON 5ALPHA-CHOLEST-8(14)-EN-3BETA-OL-15-ONE, A POTENT HYPOCHOLESTEROLEMIC AGENT
Institution: | Rice University |
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Department: | |
Year: | 1980 |
Keywords: | Biochemistry |
Record ID: | 1509957 |
Full text PDF: | http://hdl.handle.net/1911/15567 |
Part 1. 5(alpha)-Cholest-8(14)-en-3(beta)-ol-15-one, prepared by chemical synthesis, was administered to male rats at a concentration of 0.1% in a low ((TURNEQ)0.005%) cholesterol diet. These rats showed a sustained decrease in food consumption and a concomitant decrease in body weight. The me