AbstractsBiology & Animal Science

METABOLIC STUDIES ON 5ALPHA-CHOLEST-8(14)-EN-3BETA-OL-15-ONE, A POTENT HYPOCHOLESTEROLEMIC AGENT

by DANIEL JOSEPH MONGER




Institution: Rice University
Department:
Year: 1980
Keywords: Biochemistry
Record ID: 1509957
Full text PDF: http://hdl.handle.net/1911/15567


Abstract

Part 1. 5(alpha)-Cholest-8(14)-en-3(beta)-ol-15-one, prepared by chemical synthesis, was administered to male rats at a concentration of 0.1% in a low ((TURNEQ)0.005%) cholesterol diet. These rats showed a sustained decrease in food consumption and a concomitant decrease in body weight. The me