a Study of the Hantzsch Pyridine Synthesis.
Institution: | McGill University |
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Department: | Department of Chemistry. |
Degree: | MS. |
Year: | 1952 |
Keywords: | Chemistry.; |
Record ID: | 1484802 |
Full text PDF: | http://digitool.library.mcgill.ca/thesisfile108627.pdf |
The objective of this thesis was to determine the value of Hantzsch pyridine synthesis in its application to the condensation of formaldehyde, acetaldehyde, n-butyraldehyde, and benzaldehyde with ethyl acetoacetate and ammonia to obtain the corresponding pyridine derivatives. Further, this method was extended to the reaction of anisic aldehyde with ethyl acetoacetate and ammonia to produce the 4-anisyl-2, 6-dimethyl-pyridine.