AbstractsChemistry

a Study of the Hantzsch Pyridine Synthesis.

by Allan T. Sabean




Institution: McGill University
Department: Department of Chemistry.
Degree: MS.
Year: 1952
Keywords: Chemistry.;
Record ID: 1484802
Full text PDF: http://digitool.library.mcgill.ca/thesisfile108627.pdf


Abstract

The objective of this thesis was to determine the value of Hantzsch pyridine synthesis in its application to the condensation of formaldehyde, acetaldehyde, n-butyraldehyde, and benzaldehyde with ethyl acetoacetate and ammonia to obtain the corresponding pyridine derivatives. Further, this method was extended to the reaction of anisic aldehyde with ethyl acetoacetate and ammonia to produce the 4-anisyl-2, 6-dimethyl-pyridine.