AbstractsBiology & Animal Science

P450 biochips : development of a protein microarray platform for investigating cytochrome P450 clinical drug metabolism

by Natasha. Beeton-Kempen




Institution: University of Cape Town
Department:
Degree: PhD
Year: 2010
Keywords: Molecular and Cell Biology
Record ID: 1481788
Full text PDF: http://hdl.handle.net/11180/1609


Abstract

Includes abstract. This thesis describes the development of a novel cytochrome P450 array format, the P450 Biochip that allows quantitative and truly high-throughput measurement of cytochrome P450-mediated turnover reactions in sub-nanolitre volumes.