P450 biochips : development of a protein microarray platform for investigating cytochrome P450 clinical drug metabolism
Institution: | University of Cape Town |
---|---|
Department: | |
Degree: | PhD |
Year: | 2010 |
Keywords: | Molecular and Cell Biology |
Record ID: | 1481788 |
Full text PDF: | http://hdl.handle.net/11180/1609 |
Includes abstract. This thesis describes the development of a novel cytochrome P450 array format, the P450 Biochip that allows quantitative and truly high-throughput measurement of cytochrome P450-mediated turnover reactions in sub-nanolitre volumes.