AbstractsBiology & Animal Science

HIV-1 infection in macrophages and genes involved throughout: Big eaters versus small invaders

by V. Cobos Jiménez




Institution: Universiteit van Amsterdam
Department:
Year: 2014
Record ID: 1260172
Full text PDF: http://hdl.handle.net/11245/1.416130


Abstract

In this thesis we have studied the infectious process of HIV-1 in differently polarized macrophages. The purpose of this research was to identify cellular factors that are involved in HIV-1 infection of macrophages, how these factors affect viral replication and whether their function or expression is affected by stimulatory signals that macrophages encounter during their differentiation in the tissues.