In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function
Institution: | Vrije Universiteit Amsterdam |
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Department: | |
Year: | 2015 |
Keywords: | GPCRs; virtual screening; membrane proteins; transmembrane proteins; computer-aided drug design; chemogenomics; functional selectivity; histamine receptor; adrenoceptor; antihistamine; site-directed mutagenesis; structure-affinity relationship; protein-ligand interactions; GPCR crystal structures |
Record ID: | 1258076 |
Full text PDF: | http://hdl.handle.net/1871/52308 |
Leurs, R. [Promotor] Esch, I.J.P. de [Promotor] Graaf, C. de [Copromotor]