AbstractsBiology & Animal Science

Heterologous expression studies of therapeutically important protein streptokinase in escherichia coli;

by Suthakaran P




Institution: Anna University
Department: Heterologous expression studies of therapeutically important protein streptokinase in escherichia coli
Year: 2015
Keywords: escherichia coli; faculty of technology; Heterologous
Record ID: 1210586
Full text PDF: http://shodhganga.inflibnet.ac.in/handle/10603/38890


Abstract

Streptokinase is an extracellular protein produced by various strains newlineof hemolytic Streptococci It is a potent thrombolytic agent comprising of newline414 amino acid and mass of about 47 kDa which is used to treat acute newlinemyocardial infarction Streptokinase is an indirect plasminogen activator newlinewhich binds with free circulating plasminogen to form a complex 11 that newlinecan convert the plasminogen to plasmin which inturn dissolves the blood newlineclot Urokinase tissue plasminogen activators are the other thrombolytic newlineagents Purification of urokinase from mammalian urine is a tedious process newline newline%%%Reference p.120-135