AbstractsBiology & Animal Science

The increase of bacteria resistance to the conventional antibiotics has led scientists to focus their research on discovering new antimicrobial agents in order to eradicate this pressing global health issue. Antimicrobial peptides and their mimics are the leading answers to this problem. This report will investigate the relationship of one antimicrobial mimic; a peptoid and its mode of action with respect to bacteria, in this case E. coli. By analysing the effect of a known antibiotic, a studied antimicrobial peptide and a tested unknown analogous peptoid, the killing kinetics were assessed, by comparing Live/Dead Quantification assay and CFU counts. The findings show evidence that there might be a difference of the mode of action between these antimicrobial agents depending on the quantity used.