The content of this paper revolves around the interrelation between science and philosophy. With a focus on Quantum Mechanics as the scientific frame of thought, we analyze the physicists’ ontological and epistemological view of reality in regards to this frame. This analysis is constructed in the time setting of the early to mid-20th century and involves a famous debate between the camps of Albert Einstein and Niels Bohr, forerunners in the field of physics at the time. We will present quantum theory, realism theory, and the pertinent physicist’s views in these regards by way of descriptive and constructive analysis. We conclude that science and philosophy are two subjects that constantly interact and that the important development of well-rounded philosophical constructions and scientific theories that coincide, or at least co-exist, with one another can only be achieved by practitioners of both.