AbstractsBiology & Animal Science

Multiscale Simulation and Analysis of Structured Ribonucleic Acids

by Benjamin Lutz




Institution: Universität Karlsruhe
Department:
Year: 2014
Keywords: Biophysics, RNA, Folding, Structure
Record ID: 1099276
Full text PDF: http://digbib.ubka.uni-karlsruhe.de/volltexte/documents/3152925


Abstract

I present the results of three projects in the course of my scientific work in the context of native structure-based models (SBMs) for regulatory RNA. They comprise a new and openly accessible software implementation of native structure-based model generation and evaluation, a study that employs a multiscale model to investigate cotranscriptional riboswitch folding and advances to a novel approach in the field of RNA tertiary structure prediction.