Multiscale Simulation and Analysis of Structured Ribonucleic Acids
Institution: | Universität Karlsruhe |
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Department: | |
Year: | 2014 |
Keywords: | Biophysics, RNA, Folding, Structure |
Record ID: | 1099276 |
Full text PDF: | http://digbib.ubka.uni-karlsruhe.de/volltexte/documents/3152925 |
I present the results of three projects in the course of my scientific work in the context of native structure-based models (SBMs) for regulatory RNA. They comprise a new and openly accessible software implementation of native structure-based model generation and evaluation, a study that employs a multiscale model to investigate cotranscriptional riboswitch folding and advances to a novel approach in the field of RNA tertiary structure prediction.