AbstractsBiology & Animal Science

Developing novel analgesics to treat chronic pain: inhibiting voltage gated sodium channel 1.7 with spider-venom peptides

by Darshani Rupasinghe Arachchilage




Institution: University of Queensland
Department: Institute for Molecular Bioscience
Year: 2015
Keywords: Chronic pain; Analgesic, NaV1.7; Structure activity relations; Pharmacophore; Alanine scan mutagenesis; Tethered toxins; Two electrode voltage clamp; Three-dimensional structure; Electrophysiology
Record ID: 1067210
Full text PDF: http://espace.library.uq.edu.au/view/UQ:349823


Abstract