Electrochemical studies toward proteomic analysis
Institution: | Curtin University of Technology |
---|---|
Department: | Chemistry |
Year: | 2014 |
Record ID: | 1050536 |
Full text PDF: | http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=199967&local_base=gen01-era02 |
This thesis provides the basis for a label-free bioanalytical platform using electrochemical analysis at liquid –liquid interfaces. The possibility to detect biomolecules such as proteins in a label-free manner via adsorption and ion-transfer was achieved. Several pre-treatment steps used in proteome analysis, such as protein pre-concentration and digestion, were studied. The results demonstrate the promise of this strategy for the detection and identification of proteins.